I have severe Neuropathy from both PPPs and Diabetes, and have tried all the so-called meds that the Drs use. As I am also diabetic my Endocrinologist put me on Metanx, and got almost immediate relief. I have been taking it twice a day for several years now, and it still is doing the job. The only problem I have is it is not covered by health insurance or Medicare. I have been able to get my RX filled at Brand Direct Health in Louisiana for substantially less than the $400 -$500 that regular pharmacies charge. Metanx has saved my sanity. If you try it, please be aware that Walgreen, CVS, etc try to give you a "generic" equivalent made in China. DO NOT accept it. It is NOT equivalent and DOES NOT WORK!
Be aware that Metanx is a combo of Metafolin, methyl B12, and B6 -- three supplements that you can buy OTC relatively cheaply.
Thanks Dan, I will look into it. remember the important thing is it works.